AN ENSEMBLE MACHINE LEARNING MODEL FOR THE PREDICTION OF DANGER ZONES: TOWARDS A GLOBAL COUNTER-TERRORISM


Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma

Introduction: Hyperactivated histone deacetylases (HDACs) act as epigenetic repressors on gene transcription and are frequently observed in human hepatocellular carcinoma (HCC).Although multiple pharmacological HDAC inhibitors (HDACis) have been developed, none is available in human HCC.Objectives: To investigate the pharmacological effects of a fa

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The Subcalcaneal Fat Pad: An Innovative Space for Passage of the Pedicle in Free Flap Reconstruction of Lateral Heel Defects

Summary:.Soft-tissue defects of the lateral heel Ringette - Cages remain a challenge for reconstructive surgeons.Although a reliable vascular supply for free flap anastomosis is available anteriorly from the anterior tibial vessels and medially from the posterior tibial vessels, the vascular anatomy of the lateral side lacks suitable donor vessels

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